Ledisa is not investing in YouTube or Demand Gen today — the only attempt spent $1,297 over 14 days (Nov 2025) and 7 of 8 campaigns never served an impression. That test proves nothing in either direction. What the data does prove: demand creation works on this brand, and today one network does 77% of it. This page is the evidence plus three full campaign proposals.
AppLovin's daily spend moves together with next-day brand searches on Google, which the brand campaigns and PMax then convert at $3.88–6.77 CPA. The mechanism a YouTube investment would exploit is already working — just owned by a single network today.
Any AppLovin shock — CPM inflation, inventory policy change, attribution change — hits three quarters of acquisition at once. A second demand channel is insurance for the whole business, not an experiment for its own sake.
Among the direct GLP-1/berberine patch competitors, the YouTube layer is almost entirely affiliate "scam or legit" reviews — only Kind Patches (the category's social leader) runs brand-owned channels with sponsored Shorts. No competitor was confirmed running paid YouTube/Demand Gen video ad campaigns. That is real, defensible whitespace for owned demand creation. Details →
We checked each competitor for a brand-owned YouTube channel and for organic/affiliate video presence via search. Confirmed: Purisaki, Lipovia, Ozempatch, Gentle and Patched have no brand-owned channel — their YouTube layer is third-party reviews and skeptic content; Kind Patches is the exception (US + UK brand channels). Adjacent wellness-patch brands (The Good Patch, Barrière, Nutri-Patch, Klova) do run brand channels. Still open and worth a manual check before launch: whether any competitor runs paid Google Ads Demand Gen / YouTube video campaigns — that requires the Google Ads Transparency Center (adstransparency.google.com) per domain, which we recommend reviewing as a pre-launch step. Net: the video-ad lane looks open, but treat "clear air" as probable, not proven.
| Ad group | Audience | Landing (already built — reused from Search) | Creative angle |
|---|---|---|---|
| AG_InMarket_WeightLoss | In-market: weight loss & supplements | Feel Full Sooner advertorial | Appetite science: "feel full sooner" |
| AG_Custom_GLP1_Searchers | Custom segment: people who searched GLP-1 / Ozempic-alternative terms | Top 5 Berberine advertorial | "Patch vs pill" ingredient science |
| AG_Affinity_Wellness40 | Health & wellness affinity, women 35–60 | Weight Gain After 40 advertorial | Routine/lifestyle, problem-first story |
| AG_Lookalike_Purchasers | Lookalike of the purchaser customer list | Store (ledisa.com PDP / bundle page) | Social proof + bundle offer |
Every advertorial here is the same page already built for Search (see the Landing Library) — one build, two channels. No separate Demand Gen creative needed.
| Ad group | Audience | Message / offer |
|---|---|---|
| AG_RMK_SiteVisitors_30d | ledisa.com + tryledisa.com visitors, 30d, non-buyers | Reminder + strongest social proof; store landing |
| AG_RMK_CartAbandoners_14d | Add-to-cart / begin-checkout, 14d, non-buyers | Offer completion + guarantee emphasis ("90-day, no questions") |
| AG_RMK_AdvertorialReaders_14d | myhealthyshape.com advertorial readers who never reached the store | "Still comparing?" — comparison recap + discount; requires the Google tag/audience on the advertorial domain (small setup task, big list) |
| AG_RMK_PastBuyers_CrossSell | Purchasers 30–180d | Cross-sell the catalog (Sleep / NAD+ / Energy patches) — feeds the repeat-revenue engine (52% of orders are returning customers) |
| Ad group | Audience | Communication angle | Click-through landing | Formats |
|---|---|---|---|---|
| AG_YT_InMarket_WL | In-market weight loss & supplements | "The needle-free routine" — what a patch morning looks like; comparison energy without drug claims | Feel Full Sooner | 30s in-stream + 15s Shorts |
| AG_YT_Custom_Alternatives | Custom segment: GLP-1 / Ozempic-alternative searchers | "How transdermal works" — absorption science explainer, ingredient transparency | Top 5 Berberine | 45–60s explainer + 6s bumpers |
| AG_YT_Affinity_Women40 | Wellness affinity women 35–60 + life events | "After 40, it's different" — hormonal-change story, day-in-the-life UGC | Weight Gain After 40 | 30s UGC + 15s Shorts |
| AG_YT_ChannelPlacements | Placement targeting: wellness/menopause/health YouTube channels | Soft education — "what we put in the patch and why" founder-style | Store + Reviews | 30s + 6s bumper |
Same recycling principle: each YouTube ad group drives to a landing already built for Search (see the Landing Library). Video creates the demand; the matching advertorial closes it.